Colorado’s tech and innovation scene continues to climb. From Boulder’s biotech breakthroughs to Denver’s cloud and AI leaders, the state blends entrepreneurial spirit with a deep sense of purpose. Below are fast-growing companies solving complex problems in health, energy, aerospace, and software while building workplaces that value creativity and collaboration.
Here’s a look at the organizations defining Colorado’s next era of innovation and proving that meaningful work and growth can thrive in the same place.
Top Companies to Watch in Denver
Crusoe
Crusoe combines GPU-cloud services, energy-aware data-centers, and software tools for large-scale machine-learning workloads to provide its customers with vertically-integrated AI infrastructure. In October 2025, it closed a Series E round earmarked at $1.3-1.38 billion and accelerated campus build-out for high-density compute environments. As demand for AI infrastructure accelerates, Crusoe’s model aligns tightly with that trend.
Strive Health
Strive Health partners with payers and providers to deliver value-based kidney-care services, leveraging data analytics and coordinated teams to improve outcomes while reducing costs. It raised $550 million in September 2025 across equity and debt financing to scale operations and deploy AI-enabled care tools. The convergence of healthcare value models and growth capital makes Strive particularly noteworthy.
Guild
Guild collaborates with employers to offer upskilling and credentialing programs that support worker mobility and internal talent pipelines. In 2025, the company marked a decade of impact and reported nearly 100,000 career transitions among participants and expanded its learning marketplace. With workforce-education intersections becoming strategic for employers, Guild stands at an important inflection.
Vantage Data Centers
Vantage Data Centers designs and operates hyperscale campuses globally, catering to cloud providers, AI workloads, and enterprise clients with high-efficiency infrastructure. In August 2025, it disclosed a $25 billion, 1.4-gigawatt Texas campus project backed by large-scale project financing. With compute demand surging and infrastructure bottlenecks growing, Vantage’s scale and pipeline give it a structural advantage.

Red Canary
Red Canary offers managed detection and response across endpoint, identity, and cloud environments. They bundle human-led threat investigations with proprietary security tooling. In FY 2025, the company reported 63 percent year-over-year enterprise bookings growth and surpassed $140 million in annual recurring revenue while expanding into identity threat detection. That growth plus strategic expansion into identity signals momentum at the intersection of cloud security and enterprise defense.
Pax8
Pax8 runs a cloud-commerce marketplace that enables managed service providers and vendors to discover, bundle, and manage cloud solutions through a unified platform. It launched an “Agent Store” designed to enable repeatable AI-powered services for its channel partners this year, and highlighted major announcements at its annual “Beyond” event.

SonderMind
SonderMind connects people with therapy and psychiatry through a blend of virtual and in-person care, applying measurement-based methods to improve outcomes. It introduced a suite of clinically-backed AI tools designed to accelerate therapy progress and drive value-based care in October 2025. By marrying tech with behavioral-health delivery, SonderMind is well-placed in a growing segment of health-tech.
StackHawk
StackHawk integrates dynamic application and API security testing into CI/CD pipelines, enabling dev teams to shift left and discover vulnerabilities earlier. It released “Sensitive Data Identification” for high-risk APIs and introduced LLM-driven OpenAPI generation, boosting coverage and automation this year, making it one to watch.

Ping Identity
Ping Identity provides enterprise identity and access-management solutions — including SSO, MFA, and access governance — for hybrid environments. In September 2025, it rolled out an AI-driven trust framework and released agent-less identity orchestration. Ping Identity has aligned its roadmap with the shift toward zero-trust and AI-augmented security.

Outrider
Outrider builds autonomous systems that move trailers within distribution yards. Their autonomous systems will replace diesel tractors with electric, self-driving units coordinated by proprietary orchestration software. The company’s $62 million Series D in 2025 is funding large-scale rollouts with logistics leaders like Georgia-Pacific and Walmart. As supply chains push for zero-emission operations and labor-efficient automation, Outrider’s technology is crossing from pilot to standard infrastructure.
Top Companies to Watch in Boulder
Enveda Biosciences
Enveda Biosciences combines AI, metabolomics, and high-throughput chemistry to mine nature’s molecular diversity and push novel medicines for immunology, obesity, and fibrotic disease. In 2025, it secured a $150 million Series D funding round, achieved unicorn status, and enrolled the first patient in its lead program ENV-294, a first-in-class oral anti-inflammatory. That level of capital plus early human data signals that the company is shifting from discovery into clinical execution in biotech.
Infleqtion
Infleqtion is developing neutral-atom quantum systems and precision sensors for applications spanning AI, national security, and space infrastructure. In September 2025, it announced a business combination with Churchill Capital Corp X that values the company at $1.8 billion and injects over $540 million to scale commercialization. With more than $29 million in trailing revenue and a pipeline exceeding $300 million in opportunities, Infleqtion is moving from lab-proof to real-world delivery.
Automox
Automox offers a cloud-native platform that automates endpoint management — patching, configuration, and policy across Windows, macOS, and Linux. Automated endpoint management allows IT teams to scale securely and efficiently. In the last year, the company rolled out its Device Details feature with hundreds of new data points and enhanced agent-tray visibility to speed remediation workflows. That proactive product evolution positions Automox to capture momentum as organizations seek unified, lightweight device management tools.
JumpCloud
JumpCloud delivers a unified cloud directory service that combines identity, access, device, and application management for hybrid workforces. It expanded its platform through the acquisition of Stack Identity and announced a roadmap that includes tighter integration of device and identity telemetry earlier this year. As identity becomes a cornerstone of modern IT-security architecture, JumpCloud’s broad platform means it’s in a strong position for growth.

Techstars
Techstars’ global accelerator programs match founders with mentors, capital, and industry networks to help early-stage companies scale. In 2025, it increased its standard investment package to $220,000 and sharpened its sector-focused programs, signaling a stronger commitment to founder development. For professionals interested in high-velocity startup ecosystems and operational roles, Techstars offers a meaningful entry point.

Boom Supersonic
Since 2014, Boom Supersonic has been developing Overture, a next-generation airliner designed for sustainable supersonic flight, and the Symphony engine to power that aircraft. In early 2025, it chose the Colorado Air & Space Port for its engine-test facility, which could signal infrastructure readiness and manufacturing scale-up. Located in Centennial, its aerospace ambitions are now meeting real-world test sites, allowing Boom to advance from concept toward build-out.
Solid Power
Solid Power, located in Louisville, develops all-solid-state battery technology for automotive and energy-storage markets, aiming for higher energy density, safety, and longevity over conventional lithium-ion cells. It has recently advanced its joint testing with an OEM partner and progressed pilot-line manufacturing milestones for high-volume cells.
Top Company to Watch in Colorado Springs

Quantum Metric
Quantum Metric delivers digital-experience analytics for web and mobile platforms, which enables product teams to measure, prioritize, and act on customer behavior data in real time. In 2025, it launched new “dimensional alerting” features to help teams surface actionable signals faster, which mirrors the broader market shift toward product-led growth. That cadence of innovation keeps the company relevant in enterprise software.